7E2O

X-ray Crystal structure of PPARgamma R288H mutant.

Summary for 7E2O

• Entry DOI: 10.2210/pdb7e2o/pdb
• Descriptor: Peroxisome proliferator-activated receptor gamma (2 entities in total)
• Functional Keywords: peroxisome proliferator-activated receptor, r288h, transcription factor, ligand binding domain, apo form, nuclear protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 62860.95

Authors

Egawa, D.,Itoh, T. (deposition date: 2021-02-06, release date: 2022-01-19, Last modification date: 2023-11-29)

• Primary citation: Egawa, D.,Ogiso, T.,Nishikata, K.,Yamamoto, K.,Itoh, T.; Structural Insights into the Loss-of-Function R288H Mutant of Human PPAR gamma.; Biol.Pharm.Bull., 44:1196-1201, 2021; PubMed: 34471047; DOI: 10.1248/bpb.b21-00253

Experimental method

X-RAY DIFFRACTION (3.2 Å)