7DWT

Cryo-EM structure of Dengue virus serotype 1 strain WestPac 74 in complex with human antibody 1C19 Fab at 37 deg C (Class 1 particle)

Summary for 7DWT

• Entry DOI: 10.2210/pdb7dwt/pdb
• Related: 7DWU
• EMDB information: 30883
• Descriptor: envelope protein, Anti-dengue virus human monoclonal antibody 1C19 Fab heavy chain, Anti-dengue virus human monoclonal antibody 1C19 Fab light chain (3 entities in total)
• Functional Keywords: dengue virus, human antibody, dengue-fab structure, virus, virus-immune system complex, virus/immune system
• Biological source: Dengue virus 1; More
• Total number of polymer chains: 5
• Total formula weight: 186485.09

Authors

Fibriansah, G.,Ng, T.S.,Kostyuchenko, V.A.,Shi, J.,Lok, S.M. (deposition date: 2021-01-18, release date: 2021-02-17, Last modification date: 2024-03-27)

• Primary citation: Fibriansah, G.,Lim, E.X.Y.,Marzinek, J.K.,Ng, T.S.,Tan, J.L.,Huber, R.G.,Lim, X.N.,Chew, V.S.Y.,Kostyuchenko, V.A.,Shi, J.,Anand, G.S.,Bond, P.J.,Crowe Jr., J.E.,Lok, S.M.; Antibody affinity versus dengue morphology influences neutralization.; Plos Pathog., 17:e1009331-e1009331, 2021; PubMed: 33621239; DOI: 10.1371/journal.ppat.1009331

Experimental method

ELECTRON MICROSCOPY (19 Å)