7DW6
SARS-CoV-2 Mpro mutant (H41A) in complex with nsp15|16 peptidyl substrate
Summary for 7DW6
Entry DOI | 10.2210/pdb7dw6/pdb |
Descriptor | 3C-like proteinase, nsp15/16 peptidyl substrate (3 entities in total) |
Functional Keywords | protease, viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) More |
Total number of polymer chains | 2 |
Total formula weight | 36033.99 |
Authors | |
Primary citation | Zhao, Y.,Zhu, Y.,Liu, X.,Jin, Z.,Duan, Y.,Zhang, Q.,Wu, C.,Feng, L.,Du, X.,Zhao, J.,Shao, M.,Zhang, B.,Yang, X.,Wu, L.,Ji, X.,Guddat, L.W.,Yang, K.,Rao, Z.,Yang, H. Structural basis for replicase polyprotein cleavage and substrate specificity of main protease from SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 119:e2117142119-e2117142119, 2022 Cited by PubMed: 35380892DOI: 10.1073/pnas.2117142119 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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