7DVB

D335N variant of Bt4394 in complex with 6SO3-NAG-oxazoline intermediate

7DVB の概要

• エントリーDOI: 10.2210/pdb7dvb/pdb
• 分子名称: Beta-N-acetylhexosaminidase, [(3~{a}~{R},5~{R},6~{S},7~{R},7~{a}~{R})-2-methyl-6,7-bis(oxidanyl)-5,6,7,7~{a}-tetrahydro-3~{a}~{H}-pyrano[3,2-d][1,3]oxazol-1-ium-5-yl]methyl sulfate, 2-acetamido-2-deoxy-6-O-sulfo-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: gh20, complex, hydrolase
• 由来する生物種: Bacteroides thetaiotaomicron
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 248435.48

構造登録者

Zhang, Z.,He, Y.,Jin, Y. (登録日: 2021-01-13, 公開日: 2022-01-19, 最終更新日: 2023-11-29)

• 主引用文献: Zhang, Z.,Dong, M.,Zallot, R.,Blackburn, G.M.,Wang, N.,Wang, C.,Chen, L.,Baumann, P.,Wu, Z.,Wang, Z.,Fan, H.,Roth, C.,Jin, Y.,He, Y.; Mechanistic and Structural Insights into the Specificity and Biological Functions of Bacterial Sulfoglycosidases; Acs Catalysis, 13:824-836, 2023; DOI: 10.1021/acscatal.2c05405

実験手法

X-RAY DIFFRACTION (2.05 Å)