7DSK

Overall structure of the LAT1-4F2hc bound with JX-075

7DSK の概要

• エントリーDOI: 10.2210/pdb7dsk/pdb
• EMDBエントリー: 30835
• 分子名称: 4F2 cell-surface antigen heavy chain, Large neutral amino acids transporter small subunit 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: lat1-4f2hc, membrane protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 131071.18

構造登録者

Yan, R.H.,Li, Y.N.,Zhang, Y.Y.,Zhong, X.Y.,Zhou, Q. (登録日: 2020-12-31, 公開日: 2021-03-10, 最終更新日: 2022-06-29)

• 主引用文献: Yan, R.,Li, Y.,Muller, J.,Zhang, Y.,Singer, S.,Xia, L.,Zhong, X.,Gertsch, J.,Altmann, K.H.,Zhou, Q.; Mechanism of substrate transport and inhibition of the human LAT1-4F2hc amino acid transporter.; Cell Discov, 7:16-16, 2021; PubMed: 33758168; DOI: 10.1038/s41421-021-00247-4

実験手法

ELECTRON MICROSCOPY (2.9 Å)