7DQ5

Crystal structure of HitB in complex with (S)-beta-phenylalanine sulfamoyladenosine

7DQ5 の概要

• エントリーDOI: 10.2210/pdb7dq5/pdb
• 分子名称: Putative ATP-dependent b-aminoacyl-ACP synthetase, [(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl ~{N}-[(3~{S})-3-azanyl-3-phenyl-propanoyl]sulfamate, CALCIUM ION, ... (4 entities in total)
• 機能のキーワード: hitachimycin, polyketide biosynthesis, atp binding, adenylation, ligase
• 由来する生物種: Embleya scabrispora
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 120416.53

構造登録者

Kudo, F.,Takahashi, S.,Miyanaga, A.,Nakazawa, Y.,Eguchi, T. (登録日: 2020-12-22, 公開日: 2021-03-03, 最終更新日: 2023-11-29)

• 主引用文献: Kudo, F.,Takahashi, S.,Miyanaga, A.,Nakazawa, Y.,Nishino, K.,Hayakawa, Y.,Kawamura, K.,Ishikawa, F.,Tanabe, G.,Iwai, N.,Nagumo, Y.,Usui, T.,Eguchi, T.; Mutational Biosynthesis of Hitachimycin Analogs Controlled by the beta-Amino Acid-Selective Adenylation Enzyme HitB.; Acs Chem.Biol., 16:539-547, 2021; PubMed: 33625847; DOI: 10.1021/acschembio.1c00003

実験手法

X-RAY DIFFRACTION (2.45 Å)