7DHI

Cryo-EM structure of the partial agonist salbutamol-bound beta2 adrenergic receptor-Gs protein complex.

Summary for 7DHI

• Entry DOI: 10.2210/pdb7dhi/pdb
• EMDB information: 30681
• Descriptor: Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total)
• Functional Keywords: g protein coupled receptor, complex, cryo-em, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 5
• Total formula weight: 151374.17

Authors

Yang, F.,Ling, S.L.,Zhou, Y.X.,Zhang, Y.N.,Lv, P.,Liu, S.L.,Fang, W.,Sun, W.J.,Hu, L.Y.A. (deposition date: 2020-11-15, release date: 2020-12-16, Last modification date: 2024-10-23)

• Primary citation: Yang, F.,Ling, S.L.,Zhou, Y.X.,Zhang, Y.N.,Lv, P.,Liu, S.L.,Fang, W.,Sun, W.J.,Hu, L.Y.A.,Zhang, L.,Shi, P.,Tian, C.; Different Conformational Responses of the beta2-Adrenergic Receptor-Gs Complex upon Binding of the Partial Agonist Salbutamol or the Full Agonist Isoprenaline; Natl Sci Rev, 2020; DOI: 10.1093/nsr/nwaa284

Experimental method

ELECTRON MICROSCOPY (3.26 Å)