7DBU

Crystal structure of catalytic domain of Anhydrobiosis-related Mn-dependent Peroxidase (AMNP) from Ramazzottius varieornatus (Zn2+-bound form)

7DBU の概要

• エントリーDOI: 10.2210/pdb7dbu/pdb
• 分子名称: AMNP/g12777, ZINC ION (3 entities in total)
• 機能のキーワード: peroxidase, manganese, tardigrade, oxidoreductase
• 由来する生物種: Ramazzottius varieornatus (Water bear)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 38205.55

構造登録者

Yoshida, Y.,Satoh, T.,Ota, C.,Tanaka, S.,Horikawa, D.D.,Tomita, M.,Kato, K.,Arakawa, K. (登録日: 2020-10-21, 公開日: 2021-10-06, 最終更新日: 2024-10-09)

主引用文献

Yoshida, Y.,Satoh, T.,Ota, C.,Tanaka, S.,Horikawa, D.D.,Tomita, M.,Kato, K.,Arakawa, K.
Time-series transcriptomic screening of factors contributing to the cross-tolerance to UV radiation and anhydrobiosis in tardigrades.
Bmc Genomics, 23:405-405, 2022

PubMed Abstract: Tardigrades are microscopic animals that are capable of tolerating extreme environments by entering a desiccated state of suspended animation known as anhydrobiosis. While antioxidative stress proteins, antiapoptotic pathways and tardigrade-specific intrinsically disordered proteins have been implicated in the anhydrobiotic machinery, conservation of these mechanisms is not universal within the phylum Tardigrada, suggesting the existence of overlooked components.

PubMed: 35643424
DOI: 10.1186/s12864-022-08642-1

実験手法

X-RAY DIFFRACTION (1.6 Å)