7DA6

Enterovirus 71 2A Protease mutant- C110A in complex with peptide inhibitor

Summary for 7DA6

• Entry DOI: 10.2210/pdb7da6/pdb
• Descriptor: Polyprotein, PHE-ARG-GLY-LYS, ZINC ION, ... (4 entities in total)
• Functional Keywords: 2a protease, viral protein
• Biological source: Human enterovirus 71 (EV71, EV-71); More
• Total number of polymer chains: 2
• Total formula weight: 15771.98

Authors

Yang, W.Z.,Yuan, H.S. (deposition date: 2020-10-15, release date: 2021-08-25, Last modification date: 2023-11-29)

• Primary citation: Chen, T.,Grauffel, C.,Yang, W.Z.,Chen, Y.P.,Yuan, H.S.,Lim, C.; Efficient Strategy to Design Protease Inhibitors: Application to Enterovirus 71 2A Protease.; Acs Bio Med Chem Au, 2022; DOI: 10.1021/acsbiomedchemau.2c00001

Experimental method

X-RAY DIFFRACTION (2.2 Å)