7D6H
Crystal structure of the SARS-CoV-2 papain-like protease (PLPro) C112S mutant
Summary for 7D6H
Entry DOI | 10.2210/pdb7d6h/pdb |
Descriptor | Papain-like protease, ZINC ION, PHOSPHATE ION, ... (4 entities in total) |
Functional Keywords | protease, deubiquitinase, viral protein, hydrolase |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) |
Total number of polymer chains | 1 |
Total formula weight | 36271.31 |
Authors | |
Primary citation | Shan, H.,Liu, J.,Shen, J.,Dai, J.,Xu, G.,Lu, K.,Han, C.,Wang, Y.,Xu, X.,Tong, Y.,Xiang, H.,Ai, Z.,Zhuang, G.,Hu, J.,Zhang, Z.,Li, Y.,Pan, L.,Tan, L. Development of potent and selective inhibitors targeting the papain-like protease of SARS-CoV-2. Cell Chem Biol, 28:855-865.e9, 2021 Cited by PubMed: 33979649DOI: 10.1016/j.chembiol.2021.04.020 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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