7D64

The crystal structure of SARS-CoV-2 3CLpro with Zinc

Summary for 7D64

• Entry DOI: 10.2210/pdb7d64/pdb
• Descriptor: 3C-like proteinase, ZINC ION (3 entities in total)
• Functional Keywords: zinc-bound, hydrolase, polyprotein processing, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
• Total number of polymer chains: 1
• Total formula weight: 33956.36

Authors

Mao, Z.W.,Xia, W.,Tao, X. (deposition date: 2020-09-29, release date: 2021-09-29, Last modification date: 2023-11-29)

• Primary citation: Tao, X.,Zhang, L.,Du, L.,Lu, K.,Zhao, Z.,Xie, Y.,Li, X.,Huang, S.,Wang, P.H.,Pan, J.A.,Xia, W.,Dai, J.,Mao, Z.W.; Inhibition of SARS-CoV-2 replication by zinc gluconate in combination with hinokitiol.; J.Inorg.Biochem., 231:111777-111777, 2022; PubMed: 35255411; DOI: 10.1016/j.jinorgbio.2022.111777

Experimental method

X-RAY DIFFRACTION (2.45011599532 Å)