7D2L
Crystal structure of the Cas12i1 R-loop complex before target DNA cleavage
Summary for 7D2L
| Entry DOI | 10.2210/pdb7d2l/pdb |
| Descriptor | 12i1-D647A, RNA (43-MER), DNA (30-MER), ... (6 entities in total) |
| Functional Keywords | the rnp complex 1, rna binding protein |
| Biological source | Lachnospiraceae bacterium ND2006 More |
| Total number of polymer chains | 4 |
| Total formula weight | 165464.41 |
| Authors | Zhang, B.,Luo, D.Y.,Li, Y.,OuYang, S.Y. (deposition date: 2020-09-16, release date: 2021-05-19, Last modification date: 2024-04-03) |
| Primary citation | Zhang, B.,Luo, D.,Li, Y.,Perculija, V.,Chen, J.,Lin, J.,Ye, Y.,Ouyang, S. Mechanistic insights into the R-loop formation and cleavage in CRISPR-Cas12i1. Nat Commun, 12:3476-3476, 2021 Cited by PubMed: 34108490DOI: 10.1038/s41467-021-23876-5 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.75 Å) |
Structure validation
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