7D1N
Crystal structure of Ixodes scapularis glutaminyl cyclase with three Cu ions bound to the active site
Summary for 7D1N
Entry DOI | 10.2210/pdb7d1n/pdb |
Descriptor | Glutaminyl-peptide cyclotransferase, COPPER (II) ION, BICARBONATE ION, ... (4 entities in total) |
Functional Keywords | glutaminyl cyclase, metal binding protein, transferase |
Biological source | Ixodes scapularis (Black-legged tick) |
Total number of polymer chains | 1 |
Total formula weight | 38563.31 |
Authors | Huang, K.-F.,Huang, J.-S.,Wu, M.-L.,Hsieh, W.-L.,Wang, A.H.-J. (deposition date: 2020-09-15, release date: 2021-04-14, Last modification date: 2023-11-29) |
Primary citation | Huang, K.F.,Huang, J.S.,Wu, M.L.,Hsieh, W.L.,Hsu, K.C.,Hsu, H.L.,Ko, T.P.,Wang, A.H. A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes. J.Mol.Biol., 433:166960-166960, 2021 Cited by PubMed: 33774034DOI: 10.1016/j.jmb.2021.166960 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.26 Å) |
Structure validation
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