7CZD

Crystal structure of PD-L1 in complex with a VHH

Summary for 7CZD

Entry DOI	10.2210/pdb7czd/pdb
Descriptor	anti-PD-L1 VHH, Programmed cell death 1 ligand 1, 1,2-ETHANEDIOL, ... (5 entities in total)
Functional Keywords	antibody, complex, vhh, immune system
Biological source	Lama glama More
Total number of polymer chains	4
Total formula weight	52703.35
Authors	Wang, C. (deposition date: 2020-09-08, release date: 2021-07-14, Last modification date: 2023-11-29)
Primary citation	Zhai, T.,Wang, C.,Xu, Y.,Huang, W.,Yuan, Z.,Wang, T.,Dai, S.,Peng, S.,Pang, T.,Jiang, W.,Huang, Y.,Zou, Y.,Xu, Y.,Sun, J.,Gong, X.,Zhang, J.,Tsun, A.,Li, B.,Miao, X. Generation of a safe and efficacious llama single-domain antibody fragment (vHH) targeting the membrane-proximal region of 4-1BB for engineering therapeutic bispecific antibodies for cancer. J Immunother Cancer, 9:-, 2021 Cited by PubMed: 34172514 DOI: 10.1136/jitc-2020-002131 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.64 Å)

Structure validation