7CXX

Structural insights into novel mechanisms of inhibition of the major b-carbonic anhydrase CafB from the pathogenic fungus Aspergillus fumigatus (disulfide-bonded form)

7CXX の概要

• エントリーDOI: 10.2210/pdb7cxx/pdb
• 分子名称: Carbonic anhydrase, ACETATE ION, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: b-class carbonic anhydrase, zinc metalloenzyme, cafb, aspergillus fumigatus, oxidative inhibition, zinc-free inactivation, lyase
• 由来する生物種: Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 52395.46

構造登録者

Jin, M.S.,Kim, S.,Yeon, J.,Sung, J.,Kim, N.J.,Hong, S. (登録日: 2020-09-02, 公開日: 2021-03-31, 最終更新日: 2023-11-29)

• 主引用文献: Kim, S.,Yeon, J.,Sung, J.,Kim, N.J.,Hong, S.,Jin, M.S.; Structural insights into novel mechanisms of inhibition of the major beta-carbonic anhydrase CafB from the pathogenic fungus Aspergillus fumigatus.; J.Struct.Biol., 213:107700-107700, 2021; PubMed: 33545350; DOI: 10.1016/j.jsb.2021.107700

実験手法

X-RAY DIFFRACTION (2 Å)