7CVY

Cryo-EM structure of Chikungunya virus in complex with Fab fragments of mAb CHK-124

Summary for 7CVY

• Entry DOI: 10.2210/pdb7cvy/pdb
• EMDB information: 30476
• Descriptor: Fab heavy chain, Fab light chain, Capsid protein, ... (5 entities in total)
• Functional Keywords: chikv, fab, complex, virus, immune system-virus complex, immune system/virus
• Biological source: Mus musculus; More
• Total number of polymer chains: 20
• Total formula weight: 632114.25

Authors

Zhou, Q.F.,Fox, J.M.,Earnest, J.T.,Ng, T.S.,Kim, A.S.,Fibriansah, G.,Kostyuchenko, V.A.,Shu, B.,Diamond, M.S.,Lok, S.M. (deposition date: 2020-08-27, release date: 2020-11-04, Last modification date: 2024-03-27)

• Primary citation: Zhou, Q.F.,Fox, J.M.,Earnest, J.T.,Ng, T.S.,Kim, A.S.,Fibriansah, G.,Kostyuchenko, V.A.,Shi, J.,Shu, B.,Diamond, M.S.,Lok, S.M.; Structural basis of Chikungunya virus inhibition by monoclonal antibodies.; Proc.Natl.Acad.Sci.USA, 117:27637-27645, 2020; PubMed: 33087569; DOI: 10.1073/pnas.2008051117

Experimental method

ELECTRON MICROSCOPY (5.2 Å)