7CMB
Crystal Structure of PAK4 in complex with inhibitor 41
Summary for 7CMB
Entry DOI | 10.2210/pdb7cmb/pdb |
Descriptor | Serine/threonine-protein kinase PAK 4, 1-(2-azanylpyrimidin-4-yl)-6-[2-(1-oxidanylcyclohexyl)ethynyl]indole-3-carboxamide (3 entities in total) |
Functional Keywords | atp binding pocket, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 33473.87 |
Authors | |
Primary citation | Song, P.,Zhao, F.,Cheng, M. Discovery of 6-ethynyl-1H-indole-3-carboxamide Derivatives as Highly Potent and Selective p21-Activated Kinase 4 (PAK4) Inhibitors to be published, |
Experimental method | X-RAY DIFFRACTION (2.592 Å) |
Structure validation
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