7CHH

Cryo-EM structure of the SARS-CoV-2 S-6P in complex with BD-368-2 Fabs

Summary for 7CHH

• Entry DOI: 10.2210/pdb7chh/pdb
• EMDB information: 30374
• Descriptor: Spike glycoprotein, BD-368-2 Fab heavy chain, BD-368-2 Fab light chain, ... (5 entities in total)
• Functional Keywords: sars-cov-2 spike, neutralizing antibody, antiviral protein-immune system complex, antiviral protein/immune system
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); More
• Total number of polymer chains: 9
• Total formula weight: 555096.83

Authors

Xiao, J.,Zhu, Q.,Wang, G. (deposition date: 2020-07-05, release date: 2020-09-16, Last modification date: 2020-11-25)

• Primary citation: Du, S.,Cao, Y.,Zhu, Q.,Yu, P.,Qi, F.,Wang, G.,Du, X.,Bao, L.,Deng, W.,Zhu, H.,Liu, J.,Nie, J.,Zheng, Y.,Liang, H.,Liu, R.,Gong, S.,Xu, H.,Yisimayi, A.,Lv, Q.,Wang, B.,He, R.,Han, Y.,Zhao, W.,Bai, Y.,Qu, Y.,Gao, X.,Ji, C.,Wang, Q.,Gao, N.,Huang, W.,Wang, Y.,Xie, X.S.,Su, X.D.,Xiao, J.,Qin, C.; Structurally Resolved SARS-CoV-2 Antibody Shows High Efficacy in Severely Infected Hamsters and Provides a Potent Cocktail Pairing Strategy.; Cell, 183:1013-1023.e13, 2020; PubMed: 32970990; DOI: 10.1016/j.cell.2020.09.035

Experimental method

ELECTRON MICROSCOPY (3.49 Å)