7CEP
Crystal structure of L-cycloserine-bound form of cysteine desulfurase SufS from Bacillus subtilis
Summary for 7CEP
| Entry DOI | 10.2210/pdb7cep/pdb |
| Descriptor | Cysteine desulfurase SufS, DI(HYDROXYETHYL)ETHER, (5-hydroxy-6-methyl-4-{[(3-oxo-2,3-dihydro-1,2-oxazol-4-yl)amino]methyl}pyridin-3-yl)methyl dihydrogen phosphate, ... (5 entities in total) |
| Functional Keywords | cysteine desulfurase, plp-dependent enzyme, cysteine metabolism, cycloserine, inhibitor, fe-s cluster biosynthesis, biosynthetic protein |
| Biological source | Bacillus subtilis subsp. subtilis str. 168 |
| Total number of polymer chains | 1 |
| Total formula weight | 47704.69 |
| Authors | Nakamura, R.,Yasuhiro, T.,Fujishiro, T. (deposition date: 2020-06-24, release date: 2021-06-30, Last modification date: 2023-11-29) |
| Primary citation | Nakamura, R.,Ogawa, S.,Takahashi, Y.,Fujishiro, T. Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms. Febs J., 2022 Cited by PubMed: 35395703DOI: 10.1111/febs.16455 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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