7CEP

Crystal structure of L-cycloserine-bound form of cysteine desulfurase SufS from Bacillus subtilis

7CEP の概要

• エントリーDOI: 10.2210/pdb7cep/pdb
• 分子名称: Cysteine desulfurase SufS, DI(HYDROXYETHYL)ETHER, (5-hydroxy-6-methyl-4-{[(3-oxo-2,3-dihydro-1,2-oxazol-4-yl)amino]methyl}pyridin-3-yl)methyl dihydrogen phosphate, ... (5 entities in total)
• 機能のキーワード: cysteine desulfurase, plp-dependent enzyme, cysteine metabolism, cycloserine, inhibitor, fe-s cluster biosynthesis, biosynthetic protein
• 由来する生物種: Bacillus subtilis subsp. subtilis str. 168
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 47704.69

構造登録者

Nakamura, R.,Yasuhiro, T.,Fujishiro, T. (登録日: 2020-06-24, 公開日: 2021-06-30, 最終更新日: 2023-11-29)

• 主引用文献: Nakamura, R.,Ogawa, S.,Takahashi, Y.,Fujishiro, T.; Cycloserine enantiomers inhibit PLP-dependent cysteine desulfurase SufS via distinct mechanisms.; Febs J., 2022; PubMed: 35395703; DOI: 10.1111/febs.16455

実験手法

X-RAY DIFFRACTION (2.05 Å)