7C85

Esterase AlinE4 mutant-S13A

7C85 の概要

• エントリーDOI: 10.2210/pdb7c85/pdb
• 分子名称: SGNH-hydrolase family esterase, CADMIUM ION, ACETATE ION, ... (4 entities in total)
• 機能のキーワード: esterase, sgnh-hydrolase family, marine, hydrolase
• 由来する生物種: Altererythrobacter indicus
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 21425.23

構造登録者

Li, Z.,Li, J. (登録日: 2020-05-28, 公開日: 2020-07-08, 最終更新日: 2023-11-29)

主引用文献

Li, Z.,Li, L.,Huo, Y.,Chen, Z.,Zhao, Y.,Huang, J.,Jian, S.,Rong, Z.,Wu, D.,Gan, J.,Hu, X.,Li, J.,Xu, X.W.
Structure-guided protein engineering increases enzymatic activities of the SGNH family esterases.
Biotechnol Biofuels, 13:107-107, 2020

PubMed Abstract: Esterases and lipases hydrolyze short-chain esters and long-chain triglycerides, respectively, and therefore play essential roles in the synthesis and decomposition of ester bonds in the pharmaceutical and food industries. Many SGNH family esterases share high similarity in sequences. However, they have distinct enzymatic activities toward the same substrates. Due to a lack of structural information, the detailed catalytic mechanisms of these esterases remain barely investigated.

PubMed: 32549911
DOI: 10.1186/s13068-020-01742-8

実験手法

X-RAY DIFFRACTION (1.75 Å)