7C5X

Crystal structure of the iota-carbonic anhydrase from eukaryotic microalga complexed with bicarbonate

7C5X の概要

• エントリーDOI: 10.2210/pdb7c5x/pdb
• 分子名称: iota-carbonic anhydrase, BICARBONATE ION (3 entities in total)
• 機能のキーワード: carbonic anhydrase, bicarbonate complex, lyase
• 由来する生物種: Bigelowiella natans
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 111214.37

構造登録者

Senda, M.,Senda, T. (登録日: 2020-05-20, 公開日: 2021-04-28, 最終更新日: 2023-11-29)

主引用文献

Hirakawa, Y.,Senda, M.,Fukuda, K.,Yu, H.Y.,Ishida, M.,Taira, M.,Kinbara, K.,Senda, T.
Characterization of a novel type of carbonic anhydrase that acts without metal cofactors.
Bmc Biol., 19:105-105, 2021

PubMed Abstract: Carbonic anhydrases (CAs) are universal metalloenzymes that catalyze the reversible conversion of carbon dioxide (CO) and bicarbonate (HCO). They are involved in various biological processes, including pH control, respiration, and photosynthesis. To date, eight evolutionarily unrelated classes of CA families (α, β, γ, δ, ζ, η, θ, and ι) have been identified. All are characterized by an active site accommodating the binding of a metal cofactor, which is assumed to play a central role in catalysis. This feature is thought to be the result of convergent evolution.

PubMed: 34006275
DOI: 10.1186/s12915-021-01039-8

実験手法

X-RAY DIFFRACTION (2.55 Å)