7C3Y

Crystal structure of the N-terminal domain of human MdmX protein in complex with Nutlin3a

Summary for 7C3Y

• Entry DOI: 10.2210/pdb7c3y/pdb
• Descriptor: Protein Mdm4, 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, 4-({(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one, ... (4 entities in total)
• Functional Keywords: mdmx, nutlin3a, oncoprotein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 11888.59

Authors

Su, Z.D.,Cheng, X.Y.,Zhang, B.L.,Kuang, Z.K.,Yang, J.,Li, Z.C.,Yu, J.P.,Zhao, Z.T.,Cao, C.Z. (deposition date: 2020-05-14, release date: 2020-06-17, Last modification date: 2023-11-29)

• Primary citation: Su, Z.D.,Cheng, X.Y.,Zhang, B.L.,Kuang, Z.K.,Yang, J.,Li, Z.C.,Yu, J.P.,Cao, C.Z.,Zhao, Z.T.; Crystal structure of the N-terminal domain of human MdmX protein in complex with Nutlin3a; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.632 Å)