7C14

Crystal structure of a dinucleotide-binding protein (Q274A) of ABC transporter endogenously bound to uridylyl-3'-5'-phospho-guanosine (Form I)

7C14 の概要

• エントリーDOI: 10.2210/pdb7c14/pdb
• 分子名称: Sugar ABC transporter, periplasmic sugar-binding protein, GLYCEROL, [(1S,3R,3aR,6aS)-3-(2-azanyl-6-oxidanylidene-1H-purin-9-yl)-5,5-bis(oxidanyl)-1,3,3a,4,6,6a-hexahydrocyclopenta[c]furan-1-yl]methyl [(2R,3S,4R,5R)-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-2-(hydroxymethyl)-4-oxidanyl-oxolan-3-yl] hydrogen phosphate, ... (6 entities in total)
• 機能のキーワード: c-di-gmp/amp, substrate-binding protein, thermus thermophilus, trna synthesis and/or modification, venus fly-trap mechanism, ugpb, transport protein
• 由来する生物種: Thermus thermophilus HB8
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 90506.79

構造登録者

Kanaujia, S.P.,Chandravanshi, M.,Samanta, R. (登録日: 2020-05-02, 公開日: 2021-03-10, 最終更新日: 2023-11-29)

• 主引用文献: Chandravanshi, M.,Samanta, R.,Kanaujia, S.P.; Structural and thermodynamic insights into the novel dinucleotide-binding protein of ABC transporter unveils its moonlighting function.; Febs J., 288:4614-4636, 2021; PubMed: 33599038; DOI: 10.1111/febs.15774

実験手法

X-RAY DIFFRACTION (2.4 Å)