7BZ5

Structure of COVID-19 virus spike receptor-binding domain complexed with a neutralizing antibody

7BZ5 の概要

• エントリーDOI: 10.2210/pdb7bz5/pdb
• 分子名称: Spike protein S1, Heavy chain of B38, Light chain of B38, ... (5 entities in total)
• 機能のキーワード: covid-19 antibody, viral protein, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 73360.00

構造登録者

Wu, Y.,Qi, J.,Gao, F. (登録日: 2020-04-26, 公開日: 2020-05-13, 最終更新日: 2023-11-29)

• 主引用文献: Wu, Y.,Wang, F.,Shen, C.,Peng, W.,Li, D.,Zhao, C.,Li, Z.,Li, S.,Bi, Y.,Yang, Y.,Gong, Y.,Xiao, H.,Fan, Z.,Tan, S.,Wu, G.,Tan, W.,Lu, X.,Fan, C.,Wang, Q.,Liu, Y.,Zhang, C.,Qi, J.,Gao, G.F.,Gao, F.,Liu, L.; A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2.; Science, 368:1274-1278, 2020; PubMed: 32404477; DOI: 10.1126/science.abc2241

実験手法

X-RAY DIFFRACTION (1.84 Å)