7BO4

Human Butyrylcholinesterase in complex with 3-(2-(butyl(2-cycloheptylethyl)amino)ethyl)-1H-indol-6-ol

7BO4 の概要

• エントリーDOI: 10.2210/pdb7bo4/pdb
• 分子名称: Cholinesterase, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total)
• 機能のキーワード: butyrylcholinesterase, complex, inhibitor, hydrolase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 63658.39

構造登録者

Brazzolotto, X.,Meden, A.,Knez, D.,Nachon, F.,Gobec, S. (登録日: 2021-01-23, 公開日: 2022-03-02, 最終更新日: 2024-01-31)

• 主引用文献: Meden, A.,Knez, D.,Brazzolotto, X.,Nachon, F.,Dias, J.,Svete, J.,Stojan, J.,Groselj, U.,Gobec, S.; From tryptophan-based amides to tertiary amines: Optimization of a butyrylcholinesterase inhibitor series.; Eur.J.Med.Chem., 234:114248-114248, 2022; PubMed: 35299116; DOI: 10.1016/j.ejmech.2022.114248

実験手法

X-RAY DIFFRACTION (2.401 Å)