7BNS

VDR complex with BXL-62

This is a non-PDB format compatible entry.

Summary for 7BNS

• Entry DOI: 10.2210/pdb7bns/pdb
• Descriptor: Vitamin D3 receptor A, Nuclear receptor coactivator 1, 1,25-Dihydroxy-16-ene-20-cyclopropyl-vitamin D3, ... (4 entities in total)
• Functional Keywords: nuclear receptor, agonist, transcription
• Biological source: Danio rerio (Zebrafish); More
• Total number of polymer chains: 2
• Total formula weight: 36263.38

Authors

Rochel, N.,Belorusova, A.Y. (deposition date: 2021-01-22, release date: 2022-03-02, Last modification date: 2024-01-31)

• Primary citation: Belorusova, A.Y.,Rovito, D.,Chebaro, Y.,Doms, S.,Verlinden, L.,Verstuyf, A.,Metzger, D.,Rochel, N.,Laverny, G.; Vitamin D Analogs Bearing C-20 Modifications Stabilize the Agonistic Conformation of Non-Responsive Vitamin D Receptor Variants.; Int J Mol Sci, 23:-, 2022; PubMed: 35955580; DOI: 10.3390/ijms23158445

Experimental method

X-RAY DIFFRACTION (2.7 Å)