7BMJ

Aspartyl/Asparaginyl beta-hydroxylase (AspH) oxygenase and TPR domains in complex with manganese, 5-fluoropyridine-2,4-dicarboxylic acid, and factor X substrate peptide fragment (39mer-4Ser)

7BMJ の概要

• エントリーDOI: 10.2210/pdb7bmj/pdb
• 分子名称: Aspartyl/asparaginyl beta-hydroxylase, Coagulation factor X, MANGANESE (II) ION, ... (5 entities in total)
• 機能のキーワード: aspartyl/asparaginyl beta-hydroxylase, dioxygenase, oxidoreductase
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 103481.15

構造登録者

Nakashima, Y.,Brewitz, L.,Schofield, C.J. (登録日: 2021-01-20, 公開日: 2021-06-02, 最終更新日: 2024-01-31)

• 主引用文献: Brewitz, L.,Nakashima, Y.,Tumber, A.,Salah, E.,Schofield, C.J.; Fluorinated derivatives of pyridine-2,4-dicarboxylate are potent inhibitors of human 2-oxoglutarate dependent oxygenases; J Fluor Chem, 247:109804-, 2021; DOI: 10.1016/j.jfluchem.2021.109804

実験手法

X-RAY DIFFRACTION (1.75 Å)