7BM4
Crystal structure of alpha Carbonic anhydrase from Schistosoma mansoni bound to 1-(4-fluorophenyl)-3-(4-sulphamoylphenyl)selenourea
Summary for 7BM4
| Entry DOI | 10.2210/pdb7bm4/pdb |
| Related | 6QQM |
| Descriptor | Carbonic anhydrase, GLYCEROL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
| Functional Keywords | lyase |
| Biological source | Schistosoma mansoni (Blood fluke) |
| Total number of polymer chains | 2 |
| Total formula weight | 77807.42 |
| Authors | Ferraroni, M.,Angeli, A.,Supuran, C.T. (deposition date: 2021-01-19, release date: 2022-03-02, Last modification date: 2024-01-31) |
| Primary citation | Angeli, A.,Ferraroni, M.,Da'dara, A.A.,Selleri, S.,Pinteala, M.,Carta, F.,Skelly, P.J.,Supuran, C.T. Structural Insights into Schistosoma mansoni Carbonic Anhydrase (SmCA) Inhibition by Selenoureido-Substituted Benzenesulfonamides. J.Med.Chem., 64:10418-10428, 2021 Cited by PubMed: 34232641DOI: 10.1021/acs.jmedchem.1c00840 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
Download full validation report
