7BH8

3H4-Fab HLA-E-VL9 co-complex

Summary for 7BH8

• Entry DOI: 10.2210/pdb7bh8/pdb
• Descriptor: HLA class I histocompatibility antigen, alpha chain E, Beta-2-microglobulin, 3H4 Fab heavy chain, ... (8 entities in total)
• Functional Keywords: antibody fab fragment mhc class i molecule human leukocyte antigen e, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 10
• Total formula weight: 193890.30

Authors

Walters, L.C.,Rozbesky, D. (deposition date: 2021-01-10, release date: 2022-04-13, Last modification date: 2024-01-31)

• Primary citation: Li, D.,Brackenridge, S.,Walters, L.C.,Swanson, O.,Harlos, K.,Rozbesky, D.,Cain, D.W.,Wiehe, K.,Scearce, R.M.,Barr, M.,Mu, Z.,Parks, R.,Quastel, M.,Edwards, R.J.,Wang, Y.,Rountree, W.,Saunders, K.O.,Ferrari, G.,Borrow, P.,Jones, E.Y.,Alam, S.M.,Azoitei, M.L.,Gillespie, G.M.,McMichael, A.J.,Haynes, B.F.; Mouse and human antibodies bind HLA-E-leader peptide complexes and enhance NK cell cytotoxicity.; Commun Biol, 5:271-271, 2022; PubMed: 35347236; DOI: 10.1038/s42003-022-03183-5

Experimental method

X-RAY DIFFRACTION (1.8 Å)