7BDV
Structure of Can2 from Sulfobacillus thermosulfidooxidans in complex with cyclic tetra-adenylate (cA4)
Summary for 7BDV
| Entry DOI | 10.2210/pdb7bdv/pdb |
| Related PRD ID | PRD_002431 |
| Descriptor | Can2, Cyclic tetraadenosine monophosphate (cA4) (3 entities in total) |
| Functional Keywords | crispr, cyclic tetra-adenylate, carf domains, nuclease, dna binding protein |
| Biological source | Sulfobacillus thermosulfidooxidans More |
| Total number of polymer chains | 6 |
| Total formula weight | 172702.64 |
| Authors | McQuarrie, S.,McMahon, S.A.,Gloster, T.M.,White, M.F.,Graham, S.,Zhu, W.,Gruschow, S. (deposition date: 2020-12-22, release date: 2021-03-03, Last modification date: 2023-12-13) |
| Primary citation | Zhu, W.,McQuarrie, S.,Gruschow, S.,McMahon, S.A.,Graham, S.,Gloster, T.M.,White, M.F. The CRISPR ancillary effector Can2 is a dual-specificity nuclease potentiating type III CRISPR defence. Nucleic Acids Res., 49:2777-2789, 2021 Cited by PubMed: 33590098DOI: 10.1093/nar/gkab073 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.02 Å) |
Structure validation
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