7BCH

Notum Fragment 772

Summary for 7BCH

Entry DOI	10.2210/pdb7bch/pdb
Related	7B84
Descriptor	Palmitoleoyl-protein carboxylesterase NOTUM, SULFATE ION, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	notum inhibitor, hydrolase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	44351.82
Authors	Zhao, Y.,Jones, E.Y. (deposition date: 2020-12-19, release date: 2022-01-12, Last modification date: 2024-01-31)
Primary citation	Zhao, Y.,Mahy, W.,Willis, N.J.,Woodward, H.L.,Steadman, D.,Bayle, E.D.,Atkinson, B.N.,Sipthorp, J.,Vecchia, L.,Ruza, R.R.,Harlos, K.,Jeganathan, F.,Constantinou, S.,Costa, A.,Kjaer, S.,Bictash, M.,Salinas, P.C.,Whiting, P.,Vincent, J.P.,Fish, P.V.,Jones, E.Y. Structural Analysis and Development of Notum Fragment Screening Hits. Acs Chem Neurosci, 13:2060-2077, 2022 Cited by PubMed: 35731924 DOI: 10.1021/acschemneuro.2c00325 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation