7B9E

Crystal structure of MurE from E.coli in complex with Z275151340

Summary for 7B9E

• Entry DOI: 10.2210/pdb7b9e/pdb
• Descriptor: UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-2,6-diaminopimelate ligase, 4-chloro-N-cyclopentyl-1-methyl-1H-pyrazole-3-carboxamide, ISOPROPYL ALCOHOL, ... (4 entities in total)
• Functional Keywords: udp-n-acetylmuramoyl-l-alanyl-d-glutamate-2, 6-diaminopimelate ligase cell wall biosynthesis ligase drug target, structural genomics, structural genomics consortium, sgc, biosynthetic protein, fragment screening
• Biological source: Escherichia coli (strain K12)
• Total number of polymer chains: 2
• Total formula weight: 107502.49

Authors

Koekemoer, L.,Steindel, M.,Fairhead, M.,Talon, R.,Douangamath, A.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,von Delft, F.,Krojer, T.,Structural Genomics Consortium (SGC) (deposition date: 2020-12-14, release date: 2020-12-23, Last modification date: 2024-01-31)

• Primary citation: Koekemoer, L.,Steindel, M.,Fairhead, M.,Talon, R.,Douangamath, A.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,von Delft, F.,Krojer, T.; Crystal structure of MurE from E.coli; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.12 Å)