7B9B
Crystal structure of human 5' exonuclease Appollo APO form
Summary for 7B9B
Entry DOI | 10.2210/pdb7b9b/pdb |
Descriptor | 5' exonuclease Apollo, NICKEL (II) ION (3 entities in total) |
Functional Keywords | dclre1b, snm1b, exonuclease, apollo, lyase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 38674.09 |
Authors | Newman, J.A.,Baddock, H.T.,Mukhopadhyay, S.M.M.,Burgess-Brown, N.A.,von Delft, F.,Arrowshmith, C.H.,Edwards, A.,Bountra, C.,Gileadi, O. (deposition date: 2020-12-14, release date: 2021-01-20, Last modification date: 2024-01-31) |
Primary citation | Baddock, H.T.,Newman, J.A.,Yosaatmadja, Y.,Bielinski, M.,Schofield, C.J.,Gileadi, O.,McHugh, P.J. A phosphate binding pocket is a key determinant of exo- versus endo-nucleolytic activity in the SNM1 nuclease family. Nucleic Acids Res., 49:9294-9309, 2021 Cited by PubMed: 34387694DOI: 10.1093/nar/gkab692 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
Download full validation report