7B8H
Monoclinic structure of human protein kinase CK2 catalytic subunit in complex with a heparin oligo saccharide
7B8H の概要
エントリーDOI | 10.2210/pdb7b8h/pdb |
分子名称 | Casein kinase II subunit alpha, 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, GLYCEROL, ... (5 entities in total) |
機能のキーワード | protein kinase ck2, casein kinase 2, catalytic subunit ck2alpha, heparin, transferase |
由来する生物種 | Homo sapiens (Human) |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 41711.09 |
構造登録者 | |
主引用文献 | Schnitzler, A.,Niefind, K. Structural basis for the design of bisubstrate inhibitors of protein kinase CK2 provided by complex structures with the substrate-competitive inhibitor heparin. Eur.J.Med.Chem., 214:113223-113223, 2021 Cited by PubMed: 33571828DOI: 10.1016/j.ejmech.2021.113223 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.34 Å) |
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