7B6Q

Crystal structure of MurE from E.coli in complex with Z57299526

Summary for 7B6Q

• Entry DOI: 10.2210/pdb7b6q/pdb
• Descriptor: UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-2,6-diaminopimelate ligase, N-[(furan-2-yl)methyl]-1H-benzimidazol-2-amine, ISOPROPYL ALCOHOL, ... (4 entities in total)
• Functional Keywords: udp-n-acetylmuramoyl-l-alanyl-d-glutamate-2, 6-diaminopimelate ligase cell wall biosynthesis ligase drug target, structural genomics, structural genomics consortium, sgc, biosynthetic protein, fragment screening
• Biological source: Escherichia coli (strain K12)
• Total number of polymer chains: 2
• Total formula weight: 107260.35

Authors

Koekemoer, L.,Steindel, M.,Fairhead, M.,Talon, R.,Douangamath, A.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,von Delft, F.,Krojer, T.,Structural Genomics Consortium (SGC) (deposition date: 2020-12-08, release date: 2020-12-23, Last modification date: 2024-01-31)

• Primary citation: Koekemoer, L.,Steindel, M.,Fairhead, M.,Talon, R.,Douangamath, A.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,von Delft, F.,Krojer, T.; Crystal structure of MurE from E.coli; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.82 Å)