7B6M

Crystal structure of MurE from E.coli in complex with Z1198948504

Summary for 7B6M

Entry DOI	10.2210/pdb7b6m/pdb
Descriptor	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-2,6-diaminopimelate ligase, 1,2-ETHANEDIOL, N-[2-(2,5-Dioxopyrrolidin-1-yl)ethyl]-3-methylbenzamide, ... (4 entities in total)
Functional Keywords	udp-n-acetylmuramoyl-l-alanyl-d-glutamate-2, 6-diaminopimelate ligase cell wall biosynthesis ligase drug target, structural genomics, structural genomics consortium, sgc, biosynthetic protein, fragment screening, structural genomics consortium for research on gene expression, sgcges
Biological source	Escherichia coli (strain K12)
Total number of polymer chains	2
Total formula weight	107371.44
Authors	Koekemoer, L.,Steindel, M.,Fairhead, M.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,von Delft, F.,Krojer, T.,Structural Genomics Consortium (SGC),Structural Genomics Consortium for Research on Gene Expression (SGCGES) (deposition date: 2020-12-07, release date: 2020-12-23, Last modification date: 2024-01-31)
Primary citation	Koekemoer, L.,Steindel, M.,Fairhead, M.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,von Delft, F.,Krojer, T. Crystal structure of MurE from E.coli To Be Published,
Experimental method	X-RAY DIFFRACTION (1.67 Å)

Structure validation