7B68

Crystal structure of MurE from E.coli in complex with Z57299526

Summary for 7B68

Entry DOI	10.2210/pdb7b68/pdb
Descriptor	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-2,6-diaminopimelate ligase, 4-[(4-methylphenyl)methyl]-1,4-thiazinane 1,1-dioxide, DIMETHYL SULFOXIDE, ... (4 entities in total)
Functional Keywords	udp-n-acetylmuramoyl-l-alanyl-d-glutamate-2, 6-diaminopimelate ligase cell wall biosynthesis ligase drug target, structural genomics, structural genomics consortium, sgc, biosynthetic protein, fragment screening
Biological source	Escherichia coli (strain K12)
Total number of polymer chains	2
Total formula weight	108178.75
Authors	Koekemoer, L.,Steindel, M.,Fairhead, M.,Talon, R.,Douangamath, A.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,von Delft, F.,Krojer, T.,Structural Genomics Consortium (SGC) (deposition date: 2020-12-07, release date: 2020-12-23, Last modification date: 2024-01-31)
Primary citation	Koekemoer, L.,Steindel, M.,Fairhead, M.,Talon, R.,Douangamath, A.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,von Delft, F.,Krojer, T. Crystal structure of MurE from E.coli To Be Published,
Experimental method	X-RAY DIFFRACTION (1.89 Å)

Structure validation