7B4X

Notum complex with ARUK3002697

Summary for 7B4X

• Entry DOI: 10.2210/pdb7b4x/pdb
• Descriptor: Palmitoleoyl-protein carboxylesterase NOTUM, SULFATE ION, DIMETHYL SULFOXIDE, ... (6 entities in total)
• Functional Keywords: notum inhibitor complex, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 44980.56

Authors

Jones, E.Y.,Fish, P. (deposition date: 2020-12-02, release date: 2022-01-12, Last modification date: 2024-01-31)

• Primary citation: Zhao, Y.,Mahy, W.,Willis, N.J.,Woodward, H.L.,Steadman, D.,Bayle, E.D.,Atkinson, B.N.,Sipthorp, J.,Vecchia, L.,Ruza, R.R.,Harlos, K.,Jeganathan, F.,Constantinou, S.,Costa, A.,Kjaer, S.,Bictash, M.,Salinas, P.C.,Whiting, P.,Vincent, J.P.,Fish, P.V.,Jones, E.Y.; Structural Analysis and Development of Notum Fragment Screening Hits.; Acs Chem Neurosci, 13:2060-2077, 2022; PubMed: 35731924; DOI: 10.1021/acschemneuro.2c00325

Experimental method

X-RAY DIFFRACTION (1.24 Å)