7B4S

Structure of the 4'-phosphopantetheinyl transferase PptAb from Mycobacterium abscessus in complex with Coenzyme A and compound 153786 from the NCI Open Database

7B4S の概要

• エントリーDOI: 10.2210/pdb7b4s/pdb
• 分子名称: Possible 4'-phosphopantetheinyl transferase, 5-[(4-chlorophenyl)methyl]-6-[[2-(dimethylamino)ethylamino]methyl]-4-oxidanyl-1~{H}-pyrimidine-2-thione, COENZYME A, ... (5 entities in total)
• 機能のキーワード: mycobacterium abscessus 4'-phosphopantetheinyl transferase complex, transferase
• 由来する生物種: Mycobacteroides abscessus ATCC 19977
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 26662.35

構造登録者

Maveyraud, L.,Carivenc, C.,Mourey, L. (登録日: 2020-12-02, 公開日: 2021-11-10, 最終更新日: 2024-01-31)

• 主引用文献: Carivenc, C.,Maveyraud, L.,Blanger, C.,Ballereau, S.,Roy-Camille, C.,Nguyen, M.C.,Genisson, Y.,Guilhot, C.,Chalut, C.,Pedelacq, J.D.,Mourey, L.; Phosphopantetheinyl transferase binding and inhibition by amidino-urea and hydroxypyrimidinethione compounds.; Sci Rep, 11:18042-18042, 2021; PubMed: 34508141; DOI: 10.1038/s41598-021-97197-4

実験手法

X-RAY DIFFRACTION (1.38 Å)