7B4R

Structure of the 4'-phosphopantetheinyl transferase PptAb from Mycobacterium abscessus in complex with Coenzyme A and N-(2,6-diethylphenyl)-N'-(N-ethylcarbamimidoyl)urea

7B4R の概要

• エントリーDOI: 10.2210/pdb7b4r/pdb
• 分子名称: Possible 4'-phosphopantetheinyl transferase, N-(2,6-diethylphenyl)-N'-(N-ethylcarbamimidoyl)urea, COENZYME A, ... (5 entities in total)
• 機能のキーワード: mycobacterium abscessus 4'-phosphopantetheinyl transferase complex, transferase, inhibition, amidino-urea
• 由来する生物種: Mycobacteroides abscessus ATCC 19977
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 26571.82

構造登録者

Maveyraud, L.,Carivenc, C.,Blanger, C.,Mourey, L. (登録日: 2020-12-02, 公開日: 2021-11-10, 最終更新日: 2024-01-31)

• 主引用文献: Carivenc, C.,Maveyraud, L.,Blanger, C.,Ballereau, S.,Roy-Camille, C.,Nguyen, M.C.,Genisson, Y.,Guilhot, C.,Chalut, C.,Pedelacq, J.D.,Mourey, L.; Phosphopantetheinyl transferase binding and inhibition by amidino-urea and hydroxypyrimidinethione compounds.; Sci Rep, 11:18042-18042, 2021; PubMed: 34508141; DOI: 10.1038/s41598-021-97197-4

実験手法

X-RAY DIFFRACTION (1.4 Å)