7B3U
OXA-10 beta-lactamase with covalent modification
Summary for 7B3U
| Entry DOI | 10.2210/pdb7b3u/pdb |
| Descriptor | Beta-lactamase OXA-10, SULFATE ION, DI(HYDROXYETHYL)ETHER, ... (5 entities in total) |
| Functional Keywords | beta lactamase, antibiotic resistance, tazobactam, dehydroalanine, irreversible inhibition, covalent modification, hydrolase |
| Biological source | Pseudomonas aeruginosa |
| Total number of polymer chains | 2 |
| Total formula weight | 56159.69 |
| Authors | Lang, P.A.,Brem, J.,Schofield, C.J. (deposition date: 2020-12-01, release date: 2022-01-12, Last modification date: 2024-01-31) |
| Primary citation | Lang, P.A.,Raj, R.,Tumber, A.,Lohans, C.T.,Rabe, P.,Robinson, C.V.,Brem, J.,Schofield, C.J. Studies on enmetazobactam clarify mechanisms of widely used beta-lactamase inhibitors. Proc.Natl.Acad.Sci.USA, 119:e2117310119-e2117310119, 2022 Cited by PubMed: 35486701DOI: 10.1073/pnas.2117310119 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.598 Å) |
Structure validation
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