7B3O

Crystal structure of the SARS-CoV-2 RBD in complex with STE90-C11 Fab

7B3O の概要

• エントリーDOI: 10.2210/pdb7b3o/pdb
• 分子名称: Spike protein S1, Light Chain of Fab Fragment, Heavy Chain of Fab Fragment, ... (5 entities in total)
• 機能のキーワード: neutralizing antibodies, sars-cov-2, rbd, antiviral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 71075.34

構造登録者

Kluenemann, T.,Van den Heuvel, J. (登録日: 2020-12-01, 公開日: 2020-12-16, 最終更新日: 2024-01-31)

• 主引用文献: Bertoglio, F.,Fuhner, V.,Ruschig, M.,Heine, P.A.,Abassi, L.,Klunemann, T.,Rand, U.,Meier, D.,Langreder, N.,Steinke, S.,Ballmann, R.,Schneider, K.T.,Roth, K.D.R.,Kuhn, P.,Riese, P.,Schackermann, D.,Korn, J.,Koch, A.,Chaudhry, M.Z.,Eschke, K.,Kim, Y.,Zock-Emmenthal, S.,Becker, M.,Scholz, M.,Moreira, G.M.S.G.,Wenzel, E.V.,Russo, G.,Garritsen, H.S.P.,Casu, S.,Gerstner, A.,Roth, G.,Adler, J.,Trimpert, J.,Hermann, A.,Schirrmann, T.,Dubel, S.,Frenzel, A.,Van den Heuvel, J.,Cicin-Sain, L.,Schubert, M.,Hust, M.; A SARS-CoV-2 neutralizing antibody selected from COVID-19 patients binds to the ACE2-RBD interface and is tolerant to most known RBD mutations.; Cell Rep, 36:109433-109433, 2021; PubMed: 34273271; DOI: 10.1016/j.celrep.2021.109433

実験手法

X-RAY DIFFRACTION (2 Å)