7B2K

Structure of the M298F mutant of the Streptomyces coelicolor small laccase T1 copper axial ligand.

7B2K の概要

• エントリーDOI: 10.2210/pdb7b2k/pdb
• 分子名称: Putative copper oxidase, COPPER (II) ION (3 entities in total)
• 機能のキーワード: small laccase, oxidoreductase, t1 copper, point mutation, m298f
• 由来する生物種: Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 74404.34

構造登録者

Zovo, K.,Majumdar, S.,Lukk, T. (登録日: 2020-11-27, 公開日: 2022-02-09, 最終更新日: 2024-01-31)

• 主引用文献: Zovo, K.,Pupart, H.,Van Wieren, A.,Gillilan, R.E.,Huang, Q.,Majumdar, S.,Lukk, T.; Substitution of the Methionine Axial Ligand of the T1 Copper for the Fungal-like Phenylalanine Ligand (M298F) Causes Local Structural Perturbations that Lead to Thermal Instability and Reduced Catalytic Efficiency of the Small Laccase from Streptomyces coelicolor A3(2).; Acs Omega, 7:6184-6194, 2022; PubMed: 35224382; DOI: 10.1021/acsomega.1c06668

実験手法

X-RAY DIFFRACTION (2.2 Å)