7AZA

Perdeuterated E65Q-TIM complexed with PHOSPHOGLYCOLOHYDROXAMATE

7AZA の概要

• エントリーDOI: 10.2210/pdb7aza/pdb
• 分子名称: Triosephosphate isomerase, PHOSPHOGLYCOLOHYDROXAMIC ACID (3 entities in total)
• 機能のキーワード: isomerase, glycolysis, tim, triosephosphate isomerase, transition state, perdeuteration
• 由来する生物種: Leishmania mexicana
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 27379.28

構造登録者

Kelpsas, V.,Caldararu, O.,von Wachenfeldt, C.,Oksanen, E. (登録日: 2020-11-16, 公開日: 2021-07-28)

• 主引用文献: Kelpsas, V.,Caldararu, O.,Blakeley, M.P.,Coquelle, N.,Wierenga, R.K.,Ryde, U.,von Wachenfeldt, C.,Oksanen, E.; Neutron structures of Leishmania mexicana triosephosphate isomerase in complex with reaction-intermediate mimics shed light on the proton-shuttling steps.; Iucrj, 8:633-643, 2021; PubMed: 34258011; DOI: 10.1107/S2052252521004619

実験手法

NEUTRON DIFFRACTION (1.8 Å)
X-RAY DIFFRACTION (1.1 Å)