7AZ3

Perdeuterated E65Q-TIM complexed with 2-PHOSPHOGLYCOLIC ACID

Summary for 7AZ3

• Entry DOI: 10.2210/pdb7az3/pdb
• Descriptor: Triosephosphate isomerase, 2-PHOSPHOGLYCOLIC ACID (3 entities in total)
• Functional Keywords: isomerase, glycolysis, tim, triosephosphate isomerase, transition state, perdeuteration
• Biological source: Leishmania mexicana
• Total number of polymer chains: 1
• Total formula weight: 27364.27

Authors

Kelpsas, V.,Caldararu, O.,von Wachenfeldt, C.,Oksanen, E. (deposition date: 2020-11-16, release date: 2021-07-28, Last modification date: 2024-05-01)

• Primary citation: Kelpsas, V.,Caldararu, O.,Blakeley, M.P.,Coquelle, N.,Wierenga, R.K.,Ryde, U.,von Wachenfeldt, C.,Oksanen, E.; Neutron structures of Leishmania mexicana triosephosphate isomerase in complex with reaction-intermediate mimics shed light on the proton-shuttling steps.; Iucrj, 8:633-643, 2021; PubMed: 34258011; DOI: 10.1107/S2052252521004619

Experimental method

NEUTRON DIFFRACTION (1.7 Å)
X-RAY DIFFRACTION (1.15 Å)