7AUM

Yeast Diphosphoinositol Polyphosphate Phosphohydrolase DDP1 in complex with 5-PCF2Am-InsP5

7AUM の概要

• エントリーDOI: 10.2210/pdb7aum/pdb
• 関連するPDBエントリー: 7AUI 7AUJ 7AUK 7AUL
• 分子名称: Diphosphoinositol polyphosphate phosphohydrolase DDP1, (1,1-difluoro-2-oxo-2-{[(1s,2R,3S,4s,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl]amino}ethyl)phosphonic acid (3 entities in total)
• 機能のキーワード: inositol, pp-insp, pyrophosphatase, polyphosphate, diadenosine polyphosphate, ddp1, nudix, hydrolase
• 由来する生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 22549.78

構造登録者

Marquez-Monino, M.A.,Gonzalez, B. (登録日: 2020-11-03, 公開日: 2021-05-19, 最終更新日: 2024-01-31)

• 主引用文献: Marquez-Monino, M.A.,Ortega-Garcia, R.,Shipton, M.L.,Franco-Echevarria, E.,Riley, A.M.,Sanz-Aparicio, J.,Potter, B.V.L.,Gonzalez, B.; Multiple substrate recognition by yeast diadenosine and diphosphoinositol polyphosphate phosphohydrolase through phosphate clamping.; Sci Adv, 7:-, 2021; PubMed: 33893105; DOI: 10.1126/sciadv.abf6744

実験手法

X-RAY DIFFRACTION (2.07 Å)