7AS7
Crystal structure of the GCD-associated TGFBIp mutant R124H
Summary for 7AS7
| Entry DOI | 10.2210/pdb7as7/pdb |
| Related | 5nv6 |
| Descriptor | Transforming growth factor-beta-induced protein ig-h3 (2 entities in total) |
| Functional Keywords | granular corneal dystrophy, lattice corneal dystrophy, protein aggregation, extracellular matrix protein, protein fibril |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 65084.32 |
| Authors | Andersen, G.R.,Gadeberg, T.A.F.,Nielsen, N.S.,Enghild, J.J. (deposition date: 2020-10-27, release date: 2020-12-23, Last modification date: 2024-01-31) |
| Primary citation | Nielsen, N.S.,Gadeberg, T.A.F.,Poulsen, E.T.,Harwood, S.L.,Weberskov, C.E.,Pedersen, J.S.,Andersen, G.R.,Enghild, J.J. Mutation-induced dimerization of transforming growth factor-beta-induced protein may drive protein aggregation in granular corneal dystrophy. J.Biol.Chem., 297:100858-100858, 2021 Cited by PubMed: 34097874DOI: 10.1016/j.jbc.2021.100858 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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