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7AR0

Co-Crystal Structure of Variant Surface Glycoprotein VSG2 in complex with Nanobody VSG2(NB19)

Summary for 7AR0
Entry DOI10.2210/pdb7ar0/pdb
DescriptorVariant surface glycoprotein MITAT 1.2, Nanobody VSG2(NB19), beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywordsvariant surface glycoprotein, epitope mapping, immune evasion, membrane protein
Biological sourceLama glama (Llama)
More
Total number of polymer chains2
Total formula weight53177.31
Authors
Stebbins, C.E.,Hempelmann, A. (deposition date: 2020-10-23, release date: 2021-11-03, Last modification date: 2024-02-07)
Primary citationHempelmann, A.,Hartleb, L.,van Straaten, M.,Hashemi, H.,Zeelen, J.P.,Bongers, K.,Papavasiliou, F.N.,Engstler, M.,Stebbins, C.E.,Jones, N.G.
Nanobody-mediated macromolecular crowding induces membrane fission and remodeling in the African trypanosome.
Cell Rep, 37:109923-109923, 2021
Cited by
PubMed: 34731611
DOI: 10.1016/j.celrep.2021.109923
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.139 Å)
Structure validation

221051

數據於2024-06-12公開中

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