Summary for 7ANQ
| Entry DOI | 10.2210/pdb7anq/pdb |
| Descriptor | Proprotein convertase subtilisin/kexin type 9, VHH P1.40 minibody anti-Cter PCSK9, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
| Functional Keywords | pcsk9, vhh p1.40, complex, hydrolase |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 2 |
| Total formula weight | 39524.16 |
| Authors | Ciccone, L.,Legrand, P.,Stura, E.A.,Dive, V.,Seidahn, N.G.,Fruchart Gaillard, C. (deposition date: 2020-10-12, release date: 2021-10-20, Last modification date: 2024-02-07) |
| Primary citation | Fruchart Gaillard, C.,Ouadda, A.B.D.,Ciccone, L.,Girard, E.,Mikaeeli, S.,Evagelidis, A.,Le Devehat, M.,Susan-Resiga, D.,Lajeunesse, E.C.,Nozach, H.,Ramos, O.H.P.,Thureau, A.,Legrand, P.,Prat, A.,Dive, V.,Seidah, N.G. Molecular interactions of PCSK9 with an inhibitory nanobody, CAP1 and HLA-C: Functional regulation of LDLR levels. Mol Metab, 67:101662-101662, 2022 Cited by PubMed: 36566984DOI: 10.1016/j.molmet.2022.101662 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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